• Mucolytic activity in acute and chronic bronchopulmonary diseases associated with bronchial secretion disorders and weakening of mucus movement.

1 tablet contains 30 mg of Ambroxol Hydrochloride.

Mucolytics.

• treatment and prophylaxis of osteoporosis in postmenopausal women for the prevention of fractures, including those of hip and spine (vertebral compression fractures);
• treatment of osteoporosis in men for the prevention of fractures;
• treatment and prophylaxis of glucocorticoid-induced osteoporosis.

1 tablet contains Sodium Alendronate, equivalent to Alendronic acid 10 mg or 70 mg.

Drugs that influence on bone structure and mineralization.

• Basic types and forms of osteoporosis (including postmenopausal osteoporosis, senile osteoporosis, steroid osteoporosis)
• Osteodystrophy due to of chronic renal insufficiency
• Hypoparathyreosis and pseudohypoparathyreosis
• Hyperparathyreosis (with bones’ lesions)
• Rickets and osteomalacia due to of malnutrition or malabsorption
• Hypophosphatemic (vitamin D-resistant) rickets and osteomalacia
• Pseudodeficient (vitamin D-dependent) rickets and osteomalacia
• Fanconi syndrome
• Renal acidosis
• Psoriasis.

• osteoporosis (postmenopausal, senile, steroid),
• osteodystrophy in chronic renal insufficiency (ChRI),
• hypoparathyreosis and pseudohypoparathyreosis (with bones affection),
• hypophosphatemic (vitamin-D-resistant) rickets and osteomalacia,
• rickets and osteomalacia associated with malnutrition or malabsorption of vitamin D,
• Fanconi syndrome (inherited renal acidosis with nephrocalcinosis,
• late osteomalacia and adiposogenital dystrophy),
• renal acidosis.

1 capsule contains Alphacalcidol 0.25 microgram and Calcium carbonate that is equivalent for 200 mg of elementary calcium.

Preparation of Vitamin D and its analogues.

Registration certificate in Ukraine № UA/9021/01/01

• The drug is indicated for adults in cases of inflammation and degenerative diseases of the musculoskeletal system, such as rheumatic arthritis, osteoarthritis (including rheumatoid arthritis), psoriatic arthritis, osteoarthrosis, ankylosing spondylitis, podagric arthritis, tendovaginitis, scapulohumeral periarthritis, bursitis, arthritis of the hip joint, knee-joint, foot and hand joints
• Osteochondrosis, cervical and lumbar spondylosis, sciatica.

• In combination with peginterferon alfa-2a or with interferon alfa-2a for the treatment of chronic hepatitis C in adult patients, in serum of which positive HCV RNA test is determined, including patients in compensation stage of cirrhosis. Combined therapy by Virorib® and peginterferon alfa-2a in patients, in which the preceding treatment by interferon alfa-2a (pegylated or non-pegylated) as monotherapy or in combination with ribavirin was ineffective.

1 capsule contains ribavirin 200 mg.

Antiviral medication of direct action.

Complex treatment of diseases caused by Biotin deficiency in adults and children older than 12 years old:

• hair diseases (high hair thinness, hair fragility, hair falling, increased greasiness or dryness of hair, grey hair);
• skin diseases (dermatitis, seborrhea oleosa, dryness and peeling of skin);
• nails diseases (fragility, exfoliation, nails growth or structure abnormality);
• gastro-intestinal tract functional disorders (including malabsorption syndrome);
• biotinidase deficiency;
• psycho-emotional disorders (expressed irritation and fatigability, somnolence, apathy, muscle weakness).

1 tablet contains Biotin 5 mg or 10 mg.

Other plain vitamin preparations. Biotin.

Paracetamol; Caffeine anhydrous; Phenylephrine HCL; Chlorpheniramine maleate

Treatment of the symptoms of grippe and acute respiratory virus diseases such as fever, headache, stuffiness in nose, rhinitis, sinusitis, sore throat, eyes pain, muscles pain, and cough.

1 tablet contains Paracetamol 500 mg; Caffeine anhydrous 30 mg; Phenylephrine HCL 10 mg; Chlorpheniramine maleate 2 mg.

Analgesic and antipyretic agents.

Registration certificate in Ukraine № UA/7630/01/01

• Superficial or deep fungal infection of skin, hair and nails, caused by dermatophytes and/or yeasts (dermatomycosis, onychomycosis, Candida perionyxis, tinea versicolor, dry dandruff, folliculitis, caused by Pityrosporum, chronic candidiasis, which affects skin and mucous membrane), if these infections can not be treated by agents for external use or they don’t reach to local therapy
• Candidiasis of oral cavity and gastrointestinal tract
• Chronic and recurrent vaginal candidiasis
• System fungal infections (system candidiasis, paracoccidioidomycosis, histoplasmosis, coccidioidomycosis blastomycosis)
• Continuation of parenteral treatment by myconazole
• Prophylactic treatment of patients with weak immunity (which was inherited or caused by disease or medicines), which have the risk of injury by fungal infections.

• Fungous skin injuries, epidermophytia inguinalis caused by Trichophton rubrum, Trichophton mentagrophytes, Microsporum canis, Epidermophyton floccosum
• Seborrheic eczema
• Tinea versicolor

• Dandruff
• Seborrheic eczema
• Tinea versicolor

Treatment and prophylaxis of fungal diseases of scalp which are accompanied with skin desquamation and itch:

• chronic and recurrent dandruff which is a manifestation of seborrhea oleosa or seborrhea sicca;
• seborrheic dermatitis;
• local pityriasis versicolor of scalp.

1 ml of shampoo contains 20 mg of ketoconazole, 48% of zink pyrithione suspension in water that is equivalent to 1% of zink pyrithione (10 mg).

Antifungal agents for external use.

• complex of dyspepsia symptoms, which is usually associated with slow gastric emptying, gastrointestinal reflux and esophagitis: abdominal fullness sense, stomach swelling sense, gastric pain;
• eructation, meteorism; nausea, vomiting; heartburn with gastric contain eructation or without it.
• nausea and vomiting of functional and organic genesis due to meal intake and caused by radiotherapy or medication therapy. Nausea and vomiting caused by dopamine agonists used for the treatment of Parkinson's disease (levodopa, bromkriptine) are specific indications.

1 tablet contains Domperidone maleate equivalent to Domperidone 10 mg.

Prokinetic agent.

• 1 film coated tablet contains Atorvastatin calcium which is equivalent to 10 mg or 20 mg of Atorvastatin.

Drugs for reducing the level of cholesterol and triglyceride in blood serum. HMG-CoA reductase inhibitors.

• Moderate and severe reflux-esophagitis.
• Helicobacter pylori eradication in patients with peptic ulcer caused by this microorganism in combination with definite antibiotics.
• Duodenal ulcer.
• Gastric ulcer.
• Zollinger-Ellison syndrome and other pathological hypersecretory states.

1 tablet contains Pantoprazole Sodium Sesquihydrate which is equivalent to Pantoprazole 40 mg.

Drugs for peptic ulcer treatment, proton pump inhibitors.

• Dermatomycosis
• Yeast dermatitis’
• Candidosis
• Coccidioidomycosis
• Histoplasmosis
• Aspergillosis
• Cryptococcosis

• Treatment of arterial hypertension and chronic cardiac insufficiency (as component of complex therapy) in a case of the inefficiency (intolerance) of treatment with angiotensin-converting enzyme (ACE) inhibitors.

1 film coated tablet contains Losartan potassium 25 mg or 50 mg.

Simple medications of angiotensine II receptors antagonists

• Kofol syrup is effective for dry and wet cough at presence of infections in the top respiratory path, angina, adenoiditis, pharyngitis, rhinitis, nasal catarrh

The preparation is well transferred by all patients, including children. Any side effects were not observed.

Registration certificate in Ukraine № UA/0101/03/01

• Symptomatic treatment of seasonal allergic rhinitis (hay fever). allergic rhinitis caused by pets, dust, cool, etc.
• Allergic conjunctivitis, allergic dermatitis, urticaria, including the chronic idiopathic urticaria.

1 film coated tablet contains Levocetirizine hydrochloride 5 mg.

Antihistaminic medications for system use

Registration certificate in Ukraine № UA/7939/01/01

• Active phase of rheumatoid arthritis in adults
• Active phase of psoriatic arthritis
• Active ingredient: Leflunomide 20 mg

Immunosuppressors.

Registration certificate in Ukraine № UA/6367/01/02

• Primary prophylaxis of myocardial infarction in patients with stenocardia; secondary prophylaxis of myocardial infarction; thrombosis and embolism prophylaxis, including increased risk of their appearance (after surgical interventions on vessels and coronary bypass surgery); prophylaxis of disturbance of cerebral blood flow by ischemic type.

1 coated tablet contains Acetylsalicylic acid 75 mg.

Anti-thrombotic agents.

Registration certificate in Ukraine № UA/9202/01/01

• Diarrhea, meteorism, spastic pain and abdominal discomfort
• Acute and chronic noninfectional diarrhea
• Diarrhea of traveler
• Syndrome of irritation bowels
• Normalization of stool in patients with iliostoma

1 tablet contains Loperamide Hydrochloride 2.0 mg, Simethicone 125.0 mg.

Combined antidiarrheal agent.

Registration certificate in Ukraine No UA/7643/01/01

• Acute pain.
• Symptomatic treatment of osteoartrosis with pain syndromes.
• Primary dismenorrhea.

1 tablet contains Nimesulide 100 mg.

Nonsteroidal anti-inflammatory and anti-rheumatic drugs.

Registration certificate in Ukraine № UA/7649/02/01

• Osteoarthritis (including the rheumatoid arthritis), osteoarthrosis, ankylosing spondylitis, bursitis, tendonitis
• Pain syndromes, caused by inflammatory, degenerative-dystrophic and traumatic damages of the vertebral column; posttraumatic and postoperative pain syndromes, caused by the inflammation and oedema of the tissue
• Painful muscular spasms because of the diseases of spinal column (cervical and lumbar syndrome) ), and after surgical operation in orthopedy and traumatology
• Skeletal muscles spasm in neurologic diseases (disseminated sclerosis, cerebral palsy, degenerative diseases of the spinal cord)
• Gynaecological diseases, which are accompanied by inflammation and pain syndromes: primary algodismenorrhea, adnexitis.

1 tablet contents 100 mg of nimesulide and 2 mg of tizanidine hydrochloridum (equivalent of tizanidine).

Nonsteroidal anti-inflammatory and anti-rheumatic drugs.

Registration certificate in Ukraine No UA/4240/01/02

• Inflammatory and degenerative forms of diseases of musculoskeletal system, which are accompanied by pain and swelling (oedema) such as:
• Rrheumatic and rheumatoid arthritis
• Podagric (GOUTY) and psoriatic arthritis’s
• Ankylosing spondylitis (Bechterew’s diseases)
• Reiter’s syndrome
• Osteoarthritis
• Bursitis, myositis, tendonitis, tendosynovitis
• Osteochondrosis with radicular syndrome
• Myelgia, neuralgia, lumbosacral radiculitis, lumbago
• posttraumatic inflammation of soft tissues and musculoskeletal system (damages and ruptures of ligaments, sprains and hurts of muscles)
• pain, caused by hard physical activity

Registration certificate in Ukraine № UA/4240/02/01

• Inflammatory and degenerative forms of rheumatic diseases of joints and cartilage tissues:
• osteoarthritis, osteoarthrosis, ankylosing spondylitis, bursitis, tendonitis;
• Pain syndromes, caused by inflammatory, degenerative-dystrophic and traumatic damages of the vertebral column
• Posttraumatic and postoperative pain syndromes, caused by inflammation and tissue oedema
• Gynaecological diseases accompanied by inflammation and pain syndromes: primary dysmenorrhoea, adnexitis
• Inflammatory diseases of ENT organs, teeth and gums, accompanied by painful feelings pharyngitis, tonsillitis, otitis, thrush, gingivitis

Registration certificate in Ukraine No UA/4240/03/01

• Treatment of infections caused by sensitive microorganisms, such as:
• infections of respiratory tract (including acute bronchitis, exacerbation of chronic bronchitis, chronic purulent bronchitis, bronchiectasis, ganglia fibrosis, pneumonia);
• infection of kidneys and urinary tract infection (including acute pyelonephritis, cystitis, ureteritis, chronic infection of urinary tract);
• Infections of upper respiratory tract (including severe sinusitis, acute and unspecified otitis media, tonsillitis);
• Infections of skin and soft tissues
• Infections of bones and joins;
• Infections of gastrointestinal tract;
• Post operative infections;
• nfections of urogenital tract (including gonorrhoea, bacterial prostatitis, adnexitis, endometritis).

1 tablet contains of Gatifloxacin sesquihydrate equivalent to Gatifloxacine 200 mg or 400 mg

Registration certificate in Ukraine No UA/7652/01/01

• Trichomoniasis (urino-genital infections in male and female, caused by Trіchomonas vagіnalіs)
• Amebiasis (all of intestinal diseases, caused by Entamoeba hіstolytіca, including amebic dysentery, all of abenteric forms of the amebiasis, especially amebic abscess of the liver)
• Lambliasis, prophylaxis of infections, caused by anaerobic bacteria in gynecology and colon operations.

Registration certificate in Ukraine № UA/7654/01/01

• Urogenital system diseases: acute and chronic pyelonephritis, prostatitis, cystitis, epididymite, complicated or recurrent urinary tracts infections, gynecological diseases
• Illnesses transmitted by a sexual way, caused by penicillin resistant gonococcus, clamydia, trichomonads and other microorganisms
• Abdominal cavity and biliary tracts infections, amebiasis - amebic dysentery, abenteric forms of the amebiasis, especially amebic abscess of the liver; lambliasis and others infected diseases, such as typhoid, salmonellosis, shigellosis
• Orodental infections, acute necrotic ulcerative gingivitis
• Prophylaxis of the infected diseases complications in immunodeficiency patients or in patients with the granulocytopenia
• Preoperative prophylaxis or afteroperative treatment of surgery infections, especially in gastroenterology.

Registration certificate in Ukraine № UA/7657/01/01

Pyrantel рamoate

• Helminthiasis
• Ascariasis
• Enterobiosis
• Ancylostomosis
• Necatorosis
• Trichostrongylosis

Each tablet contains Pyrantel Pamoate eq. to Pyrantel 250 mg.

Anthelmintic drugs

Registration certificate in Ukraine UA/6151/01/01

• Treatment of peptic ulcer of stomach and duodenum in case, when H. Pylori is absent or preventive treatment in case, when the eradication of H. Pylori is impossible.
• Gastroesophageal reflux
• Zollinger-Ellison syndrome
• Chronic hyperacidic hastritis in the exacerbation stage
• Non-ulcer dyspepsia.

1 tablet contains Ranitidine hydrochloride, which is equivalent to 150 mg of Ranitidine.

Agent for the treatment of peptic ulcer.

Registration certificate in Ukraine № UA/9934/01/01

• arterial hypertension (as monotherapy or as a part of combined therapy).
• ischemic heart disease (stable stenocardia and vasospastic stenocardia (Prinzmetal's angina)). The preparation can be used as monotherapy agent and in combination with other antianginal drugs.

1 tablet contains S(-)amlodipine besylate which is equivalent to S(-)amlodipine 2.5 mg and 5 mg.

Selective calcium antagonists with predominant influence on vasculars.

Serratiopeptidase

• sprain and rupture of ligaments, fractures and dislocations, edemas caused by operation;
• reducing ofsputum viscosity and facilitates its excretion from respiratory tracts;
• facilitating of excretion of accessory sinuses secretion;
• acute inflammatory dermatosis;
• haematomas, galactostasis.

1 tablet contains serratiopeptidase 10 mg.

Drugs for disorders of the musculo-skeletal system. Enzymes.

Registration certificate in Ukraine № UA/7966/01/01

• peripheric circulation disorders of different genesis: limb arteriospasm, obliterating endarteritis, limb artery atherosclerosis, diabetic angiopathy, Raynaud’s disease and syndrome;
• chronic cerebro-vascular insufficiency in genesis of atherosclerosis, atherosclerosis of retinal artery;
• threat of premature delivery (as continuation of therapy by injection isoxsuprine).

1 tablet contains іsoxsuprine hydrochloride 10 mg or 20 mg.

Peripheral vasodilator. Derivative of 2-amino-1-phenyletanol.

• acute sinusitis,
• exacerbation of chronic bronchitis,
• pneumonia,
• complicated and non-complicated urinary tract infection (including pyelonephritis),
• chronic bacterial prostatitis,
• infections of skin and soft tissues,
• septicemia/bacteriemia,
• intraabdominal infections.

1 tablet contains of Levofloxacin hemihydrate equivalent to Levofloxacin 500 mg and 750 mg.

Quinolone antibacterial drugs. Fluoroquinolone.

• pneumonia,
• complicated urinary tract infection (including pyelonephritis),
• infections of skin and soft tissues,
• septicemia/bacteriemia,
• intraabdominal infections,
• prostatitis.

1 ml of solution contains of Levofloxacin hemihydrate equivalent to Levofloxacin 5 mg.

Quinolone antibacterial drugs. Fluoroquinolone.

• approved diagnosis of the postmenopausal osteoporosis;
• renal osteodystrophy in patients with chronic renal insufficiency (ChRI),
• secondary hyperparathyreosis,
• hypoparathyreosis and pseudohypoparathyreosis (with bones affection),
• hypophosphatemic (vitamin-D-resistant) rickets and osteomalacia,
• pseudodeficient (vitamin-D-dependent) rickets and osteomalacia.

1 capsule contains 0.25 microgram of Calcitriol.

Preparation of Vitamin D and its analogues.

• Local treatment of mild and moderate degree of psoriasis.

1 g of ointment contains Calcitriol 3 microgram.

Antipsoriatic drugs for topical use.

• Approved diagnosis of the postmenopausal osteoporosis
• Secondary hypoparathyreosis and osteoporosis in patients with chronic renal insufficiency, postoperative hypoparathyreosis
• Idiopathic hypoparathyreosis
• Pseudohypoparathyreosis
• Vitamin D-dependent rickets
• Hypophosphatemic vitamin D-resistant rickets (phosphate diabetes).

Registration certificate in Ukraine No UA/0083/01/01

• Infections, which caused Candidas, including generalized candidosis, candidemia, disseminated candidosis and other forms of invasive candidal infection (infections: generalized, endocardium, eyes, respiratory and urinary tracts)
• Candidosis of mucous tunic, including oral cavity and throat, gullet candidosis, noninvasive bronchopulmonary infections
• Candiduria
• Mucocutaneous and chronic atrophic candidiasis of oral mucous tunic (because of dental prosthesis bearing)
• Genital candidosis – vaginal candidosis (acute and recurrent), vaginal candidosis recurrence prophylaxis (more than 3 cases in the year), candidal balanitis.

• Pain syndrome in inflammation and degeneration forms of rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis, osteoarthrothis, spondyloarthrothis)
• Pain syndrome in spinal diseases
• Acute podagra attack
• Posttraumatical and postoperative pain syndrome , which are accompanied by inflammation and edema
• Severe attacks of migraine
• Renal and biliary colic
• Gynecology diseases, which are accompanied by pain syndrome and inflammation (primary algodismenorrhea, adnexitis etc.)
• Severe inflammatory disease of ear, throat, nose with pain sensation (pharyngitis, tonsillitis, otitis, etc).

Each of tablets contents paracetamol – 500 mg, diclofenac sodium – 50 mg.

Registration certificate in Ukraine No UA/7260/01/01

• Local treatment of inflammatory and degenerative forms of diseases of musculoskeletal system, which are accompanied by pain and swelling such as:
• Rheumatoid arthritis,
• Ankylosing spondylitis (Bechterew’s disease)
• Acute podagric (related to gout), inflammation, psoriatic and post-traumatic arthritis
• Rheumatic damage of soft tissues (tendonitis bursitis, myositis)
• Degeneration diseases of joints (arthrosis of large and small joints)
• Osteochondritis of spinal column
• Myalgia, neuralgia, lumbosacral radiculitis
• Trauma pain , ligamentous laxity, sprain of ligaments, muscles, tendons
• Pain in muscles and joints, induced by hard physical activity.

Registration certificate in Ukraine No UA/7665/01/01